Any supplements should only to be taken while under the care of a qualified physician.
Studies vary as to how long the tick must feed on you in order to transmit disease. What we do know is the longer an infected tick is embedded in your skin the greater the chance there is to contract disease.
Since Lyme disease is a multi-systemic illness there is a multitude of symptoms associated with the illness. Some include;
Flu-like illnessFeverHistory of Tick Bite (Not all patients recall a bite)HeadacheExtreme FatigueEM Rash, Other Rashes (Only found in 50% of patients)Malar Flush, Red Ear LobesTMJ/ Jaw Pain (Temporomandibular Join)Neck & Back PainJoint Pain & Swelling, Bone Pain 
Diagnosis & Treatment
Lyme disease is a Clinical Diagnosis. Not all tests for Lyme disease are accurate, but may be helpful. You may have the infection and yet your tests can be negative due to the lack of immune response to the bacteria. Your doctor will carefully go over your medical history and symptoms.
Early appropriate treatment will increase chances of eradicating the disease and may prevent you from developing chronic Lyme disease.
Peer reviewed and published Scientific Research supports that Lyme can become chronic. In some cases Lyme disease has resulted in death of the infected individual.
A physician or qualified medical practitioner diagnoses and treats Lyme disease. Lyme disease is treated with antibiotics. Antibotics may be given orally, inter-muscularly (IM) or by intravenous therapy (IV). Only a qualified medical practitioner can prescribe your course of treatment.