COGNIFACTORS Contains N-ACETYL L-CARNITINE (ALCAR) normally produced in the mitochondria, is a precursor
of acetyl-Coenzyme A in the tricarboxylic acid (TCA) cycle. ALCAR۪s ability to
attenuate oxidative stress and prevent mitochondrial ATP depletion is why ALCAR
is considered a neuronal support compound. ALCAR protects against betaamyloid
neurotoxicity and significantly reduces oxidative damage to RNA. Electron
microscope studies of the hippocampus in old rats showed that ALCAR and or
R-Alpha Lipoic acid reversed age-associated mitochondrial structural decay. Think
of CogniFactors for your patients with mild to moderate memory impairment.
PHOSPHATIDYLSERINE (PS) enhances cholinergic function, restores Acetylcholine
release (in aging rats), and prevents age-related reduction in dendritric spine
density in the rat hippocampus. Studies have shown PS to restore Protein Kinase
C activity. PS has demonstrated some usefulness in treating cognitive impairment
and age-associated memory impairment. It is also useful in treating those patients
with well known degenerative memory impairment conditions.
NATTOKINASE is created by the bacterial fermentation of soy beans from the
bacterium Bacillus Natto. Dr. Hiroyuki Sumi discovered this enzyme, The enzyme
of enzymes. Nattokinase functions as a fibrinolytic. Daily use reduces the risk
of thrombotic events that may otherwise threaten our patients۪ lives (CVA, MI PE,
etc.). Nattokinase enhances normal circulation and oxygen perfusion to tissues.
BACOPA MONNIERA has antioxidant properties and has a long traditional Ayurvedic
use for memory enhancement. Rat studies show that Bacopa increases learning
skills and visual information processing. Human studies show that Bacopa
decreases the rate of forgetting and improves mood.
DIMETHYL AMINO ETHANOL (DMAE) is made naturally in the brain. It has been shown to alleviate behavioral problems and normalize activity levels and attention. DMAE increases attention span, decreases aggressive behavior, improves learning ability, and occasionally shows an increase in IQ (70% of those with deficient attention
span). DMAE inhibits and reverses cross-linking of proteins. Removal of age spots
(lipofuscin pigment) from skin and neurons is enhanced. Anxiety is reduced and
alertness is enhanced. Motivation is enhanced and apathy is reduced.
DMAE improves interhemispheric flow of information in the corpus callosum,
thereby improving creativity and verbal fluency. Sleep need is reduced by 1 hour
after 6 weeks of use. Dreams become more vivid and sleep is sounder and more
refreshing. DMAE enhances Acetylcholine, Choline, and RNA levels within the
brain. DMAE has a superior ability to cross the blood-brain barrier.
GINKGO BILOBA EXTRACT (GBE) is widely used as a dietary supplement for increasing
cognitive function in elderly people. Its action is through its enhanced circulation
(vasodilation) effects and its neuroprotective antioxidant qualities. Quality of GBE
varies widely. In 1999 consumer labs showed that nearly 25% of GBE brands
tested did not meet their label claims of expected chemical marker compounds
despite claims to being standardized.
VINPOCETINE increases cerebral blood flow and metabolism. Vinpocetine comes
from the plant Vinca minor and has a long standing use as an aide to cognitive
enhancement. Studies confirm its neuroprotective and antioxidant properties.
Vinpocetine may have anticonvulsant benefits.
ALPHA R LIPOIC ACID has strong antioxidant protective qualities and enhances
antioxidant recycling. ARLA also supports enhanced mitochondrial metabolism
through its support of the Krebs Citric Acid cycle and ATP production. This
antioxidant is both fat and water soluble. ARLA may slow brain aging and have
anti-aging benefits. ARLA has neuroprotective benefits. ARLA is the biologically
active form of lipoic acid and is considerably stronger than synthetic ALA (alpha
RS Lipoic Acid, racemic mixture).
HUPERZINE A from the moss Huperzia serrata, is a potent neuroprotective agent.
Huperzine A gives support for healthy cognitive function. Balancing Glutamatergic
function protects against Glutamate toxicity. Huperzine A prevents breakdown of
acetylcholine by inhibiting acetylcholinesterase enzyme activity.
Provides specific botanicals, amino acids, circulatory aides,
antioxidants, and accessory nutrients for optimal cognitive
function and memory enhancement
Enhanced neuroprotection, mitochondrial energy support,
and neurotransmitter balancing.